The scope of research carried out commercially  in the Integrated Laboratory of Experimental NeoLek -  Oncology and Innovative Technology:

In vitro research:

  • Examination of the  in vitro antiproliferative activity of  compounds or natural products of potential antitumour activity against  human and murine cells of normal and neoplastic lines
  • Pharmacokinetic and toxicological studies in vitro  (some parameters ADME/Tox)
  • Flow cytometric analysis of cell cycle, protein expression, necrosis and apoptosis
  • Analysis of protein expression by Western-blot
  • Analysis of gene expression by real-time PCR


Contact: Dr Dagmara Kłopotowska
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phone. 71 370 99 42


In vivo research:
  • Examination  of  in vivo antitumour activity of chemical compounds  or natural products in the models of human and mouse tumors transplanted into experimental mice
  • Multiparameter analysis of  murine tissues and organs
  • In vivo assessments of preliminary examination of toxicity
  • Pharmacokinetic studies in vivo


Contact: Prof. Joanna Wietrzyk
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phone. 71 370 99 85

Tekst alternatywny

Analytical and chemical research

  • Chemical modifications of macromolecules. Studies on the conjugates and drug-carrier complexes
  • Investigation of the aggregation capacity of biological macromolecules
  • Monitoring the phenomenon of oligomerization of macromolecules
  • Determination of the level of drugs and metabolites  in biological materials,  research of potential biomarkers using mass spectrometry
  • Studies of biotransformation of drugs and therapeutic agents
  • Stability studies  of potential therapeutic substances
  • Development and validation of analytical methods
  • In collaboration with industrial partners involved in the studies - innovative technologies


Contact: Prof. Janusz Boratyński
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phone. 71 370 99 80

Photo: Mateusz Psurski

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